Indication: Lomaira™ (phentermine hydrochloride USP) 8 mg tablets, CIV is a prescription medicine used for a short period of time (a few weeks) for weight reduction and should be used together with regular exercise and a reduced-calorie diet. Lomaira is for adults with an initial BMI* of 30 or more or 27 or more with at least one weight-related medical condition such as controlled high blood pressure, diabetes, or high cholesterol. The limited usefulness of this drug class (anorectics), including Lomaira, should be measured against possible risk factors inherent in their use.

Top 5 Reasons to Lose 5%

According to an article by the National Institute of Health (NIT), people classified as obese (BMI greater than 30%) can experience many benefits by reducing their weight by as little as 5%. This is great news for the over 1 in 3 Americans who fall into this category, and feel the effects of obesity on a daily basis. The benefits of a 5% weight loss can be life changing and are both physiological and psychological.

  1. Reduce the Risk of Developing Cancer

The risk of developing and dying from 13 types of cancers–including ovarian, pancreatic, and kidney–rises in people classified as obese. The American Cancer Society estimates the number of new cancer cases in the United States in 2018 to be 1.7 million, with approximately 610,000 dying from the disease.

As one gains weight and increases fat tissue, more blood vessels are needed. Obesity has been shown to affect metabolic function and disrupt the way new blood vessels form from existing ones. This can cause otherwise benign tumors to become malignant. Losing weight reduces fat tissue and helps blood vessels return to their former state. Losing as little as 5% body weight has been shown to lead to improved metabolic function in the liver, fat, and muscle.

  1. Achieve Overall Better Health

Those who experience moderate weight loss may also gain additional health-related benefits.

A study published by the American Diabetes Association showed that adults who lost 5% of their body weight had significant improvements in cardiovascular risk factors, such as a decrease in blood pressure and an increase in good cholesterol–with those who lost more weight experiencing even greater benefits.

Losing weight can also help reduce the chance of developing certain diseases. For example, obesity makes the body work harder to use insulin to control blood sugar levels, leading to the development of type-2 diabetes. Losing just 5% of one’s weight will decrease overall body fat and reduce the risk of developing the disease.

In addition, obesity is the most common cause of obstructive sleep apnea, which decreases blood oxygen and causes people to awake many times during the night. This disruption in sleep can have serious consequences including an increased chance of cardiovascular incidents, accidents, and premature death. According to a study done by the University of Pennsylvania, improving your diet and losing weight can help stave off sleep apnea. This is key to preserving healthy brain cells and keeping you more alert–which can lower the incidents of accidents and injuries.

  1. Increase Ability to Exercise Longer and More Intensely

Losing 5% can help you exercise longer and more intensely, achieving greater results. Regular exercise helps reduce stress and offers many benefits in addition to increased weight loss.

 

  • Increased energy by reducing feelings of fatigue
  • Increased happiness by helping the brain react to hormones which fight depression and producing more endorphins
  • Lower levels of certain cancer-associated hormones
  • Decreased chance of becoming insulin resistant
  • Reduced odds of catching a cold or the flu by helping rid your lungs and airways of bacteria
  • Help sleeping better, which can boost your immune system and memory function
  1. Improve Quality of Life 

Carrying extra weight can wreak havoc on both your physical and mental well-being, often leading to physical pain, fatigue, and depression.  

Extra weight means extra pressure on joints, making simple movements more difficult and sometimes quite painful. For those experiencing some types of knee pain, simply losing one pound of weight works to remove four pounds of pressure on the knees, which the Arthritis Foundation states can ease pain and inflammation.

Fatigue and associated mood changes can be common among the obese due to sleep disorders. According to a study presented at the joint meeting of the International Society of Endocrinology and the Endocrine Society, obese adults who lose as little as 5% of their weight experienced not only improved sleep after six months of weight loss but improved mood as well.

Although both men and women can experience obesity-related depression, the risk is slightly higher among women. Depression can thwart efforts to lose weight by leading to binge eating, worsening the condition. Slight changes in diet, such as safely curbing appetite, can help achieve noticeable results in a relatively short time frame and help reduce negative feelings, leading to a greater quality of life.

  1. Get Motivated to Lose More

Although losing 5% can help people look and feel better, in this case…the more the better. Seeing the changes resulting from a moderate weight loss can increase motivation to eat well and exercise, making the weight loss journey easier and more rewarding.

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INDICATION
Lomaira™ (phentermine hydrochloride USP) 8 mg tablets, CIV is a prescription medicine used for a short period of time (a few weeks) for weight reduction and should be used together with regular exercise and a reduced-calorie diet. Lomaira is for adults with an initial BMI* of 30 or more (obese) or 27 or more (overweight) with at least one weight-related medical condition such as controlled high blood pressure, diabetes, or high cholesterol. The limited usefulness of this drug class (anorectics), including Lomaira, should be measured against possible risk factors inherent in their use.

IMPORTANT SAFETY INFORMATION
Don’t take Lomaira™ if you have a history of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure or uncontrolled high blood pressure); are taking or have taken a monoamine oxidase inhibitor drug (MAOI) within the past 14 days; have overactive thyroid, glaucoma (increased pressure in the eyes), agitation or a history of drug abuse; are pregnant, nursing, or allergic to the sympathomimetic amines such as phentermine or any of the ingredients in Lomaira.

Taking phentermine with other drugs for weight loss is not recommended. Primary pulmonary hypertension (PPH), a rare fatal lung disease, has been reported in patients who had taken a combination of phentermine and fenfluramine or dexfenfluramine for weight loss. The possible association between phentermine use alone and PPH cannot be ruled out. Patients should report immediately if they experience any decrease in the amount of exercise that they can normally tolerate, shortness of breath, chest or heart pain, fainting or swelling in the lower legs.

Serious heart valve problems or disease have been reported in patients taking a combination of phentermine and fenfluramine or dexfenfluramine for weight loss. The possible role of phentermine has not been established, therefore the possibility of an association between heart valve disease and the use of phentermine alone cannot be ruled out.

If your body becomes adjusted to the maximum dose of phentermine so that its effects are experienced less strongly, the maximum dose should not be exceeded in an attempt to increase the effect.

Caution is advised when engaging in potentially hazardous activity such as driving or operating machinery while taking phentermine. Phentermine has the potential to be abused. Keep Lomaira in a safe place to prevent theft, accidental overdose, misuse or abuse. Using alcohol with phentermine may result in an adverse drug reaction.

Phentermine can cause an increase in blood pressure. Tell your doctor if you have high blood pressure, even if it’s mild. If you are taking medicines for type 2 diabetes, your doctor may have to adjust these medicines while taking phentermine.

Some side effects of phentermine that have been reported include pulmonary hypertension, valvular heart disease, palpitations, increased heart rate or blood pressure, insomnia, restlessness, dry mouth, diarrhea, constipation and changes in sexual drive. These are not all of the potential side effects of phentermine. For more information, ask your doctor or pharmacist.

To report negative side effects of prescription drugs, contact FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

*Body Mass Index (BMI) measures the amount of fat in the body based on height and weight. BMI is measured in kg/m2.

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IMPORTANT SAFETY INFORMATION Don’t take Lomaira™ if you have a history of cardiovascular disease (e.g., coronary artery disease, stroke, arrhythmias, congestive heart failure or uncontrolled high blood pressure); are taking or have taken a monoamine oxidase inhibitor drug (MAOI) within the past 14 days; have overactive thyroid, glaucoma (increased pressure in the eyes), agitation or a history of drug abuse; are pregnant, nursing, or allergic to the sympathomimetic amines such as phentermine or any of the ingredients in Lomaira.